Published scoops - Science

4

Loratadine Inhibitor

http://www.bocsci.com

Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Reference Reading
1.Effects of Prednisolone on the Pharmacokinetics of Loratadine after Oral and Intravenous Administration of Loratadine in Rats
2.Physicochemical characterization and dissolution enhancement of loratadine by solid dispersion technique

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Created by AdaBrown 1 week 16 hours ago – Made popular 5 days 5 hours ago
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4

lamotrigine inhibitor

http://www.bocsci.com

Lamotrigine is an anticonvulsant, inhibiting glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.
Molecular Weight 256.09
Molecular Formula C9H7Cl2N5
Target Sodium Channel
Reference-Concentrations of lamotrigine in a mother on lamotrigine treatment and her newborn child

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Created by AdaBrown 1 week 16 hours ago – Made popular 5 days 5 hours ago
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3

L-NAME Inhibitor

http://www.bocsci.com

L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

References:
1,Effect of low doses of L-NAME on methamphetamine-induced dopaminergic depletion in the rat striatum
2,Effect of L-arginine methyl ester (L-NAME) on hormonal profile and estrous cycle length in buffaloes (Bubalus bubalis)

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3

Ghk-cu peptides

http://www.creative-peptides.com

Copper peptide is a naturally occurring copper complex of a glycyl-L-histidyl-L-lysine peptide. It can promote activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts.

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Created by anniegggg 2 weeks 5 days ago – Made popular 2 weeks 4 days ago
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3

Glycopeptides Synthesis

http://www.creative-peptides.com

Glycopeptide has been widely recognized as peptide that contains carbohydrate moieties (glycans). Due to the nature linkage between glycan and the amino acid residues of peptide, glycopeptides can be classified into three types: N-linked, O-linked and C-linked glycopeptides. Among of them, N-linked glycopeptides are the most common type in nature, which N is referred to the asparagine that attached by the glycan. Glycan of O-linked glycopeptides is commonly linked to the hydroxyl groups of serine and threonine, while sometime also bond to lysine, proline and tyrosine. While the least common C-linked glycopeptides are recognized as the attachment between mannose and tryptophane.

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4

Calcitonin pepitde

http://www.creative-peptides.com

Calcitonin (salmon) is a 32-amino acid polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.

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4

GMP Peptide Synthesis

http://www.creative-peptides.com

We have the capacity to produce GMP peptides, APIs in annual quantities of hundreds of kilograms. The availability of low-cost active pharmaceutical ingredients from CreativePep has had a big impact on the international API manufacturers. Large scale cGMP manufacturing requires a commitment to excellence. Using CreativePep as your contract research organization and contract manufacturing organization, you get more choice, more responsiveness, and more expertise to realize your exciting drug discovery and development support.

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Created by anniegggg 2 weeks 5 days ago – Made popular 2 weeks 4 days ago
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4

IB Schools in Bangalore

https://www.trioworldacademy.com

TRIO World Academy is a global platform for learning global values imparted through excellent education of highest standard. The school educates students from nursery to higher secondary as per Cambridge IGCSE, AS, A-Level Curriculum. We are a Co-Educational International Day and Boarding School in Bangalore, India. We are ranked among the top 10 International Schools in India.

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Created by sallysingha 2 weeks 6 days ago – Made popular 2 weeks 6 days ago
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4

ICSE Schools in Bangalore

https://www.trioworldschool.com

Trio World School brings together unparalleled subject diversity and infrastructure, making it one of the best emerging ICSE schools in Bangalore. A young school based on timeless values,TRIO is one among highly sought after ICSE schools. Trio nurtures growth minded and enterprising individuals amidst an environment of harmony, the Trio way. Under the ICSE curriculum, young learners blaze their own path by dedicating themselves to disciplines that are ideal for them. They enjoy all round development through our extensive extracurricular programmes. T

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Created by sallysingha 2 weeks 6 days ago – Made popular 2 weeks 6 days ago
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3

Organic synthesis

http://www.bocsci.com

Design of new syntheses
● Chiral synthesis and resolution
● Scale-up of existing literatures or customer supplied syntheses, custom manufacturing of chemicals in bulk quantities
● Modification or replacement of poorly performing steps in a synthesis
● Design and synthesis of multipurpose screening compounds
● Molecules include but not limited to screening compounds, starting materials, building blocks, intermediates or derivatives of lead compounds
● Development and validation of analytical methods
● X-ray crystallography service

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Created by anniegggg 6 weeks 17 hours ago – Made popular 5 weeks 6 days ago
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