Published scoops - Science

7

Gadobutrol inhibitor

http://www.bocsci.com

Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). It has a macrocyclic framework and is neutral. It is a water-soluble, highly hydrophilic compound with a partition coefficient between n-butanol and buffer at pH 7.6 of ~ 0.006.

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Created by AdaBrown 1 year 37 weeks ago – Made popular 1 year 37 weeks ago
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7

6-Carboxytetramethylrhodamine

http://www.bocsci.com

6-carboxy derivatives of tetramethylrhodamine is one of the most convenient compounds of Xanthene fluorescent dye tetramethylrhodamine. 6-Carboxytetramethylrhodamine is a long-wavelength dye. Besides that, it also can be used for labeling of biomolecules, e.g., DNA, PNA, and peptides. Fluoresence: λex 543 nm, λem 575 nm in 0.1 M Tris pH 8.0; λex 540 nm, λem 565 nm in methanol; λex 555 nm, λem 580 nm; λex 541 nm, λem 568 nm in DMSO

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Created by AdaBrown 1 year 37 weeks ago – Made popular 1 year 37 weeks ago
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5

Loratadine Inhibitor

http://www.bocsci.com

Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Reference Reading
1.Effects of Prednisolone on the Pharmacokinetics of Loratadine after Oral and Intravenous Administration of Loratadine in Rats
2.Physicochemical characterization and dissolution enhancement of loratadine by solid dispersion technique

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Created by AdaBrown 1 year 42 weeks ago – Made popular 1 year 42 weeks ago
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5

lamotrigine inhibitor

http://www.bocsci.com

Lamotrigine is an anticonvulsant, inhibiting glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.
Molecular Weight 256.09
Molecular Formula C9H7Cl2N5
Target Sodium Channel
Reference-Concentrations of lamotrigine in a mother on lamotrigine treatment and her newborn child

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Created by AdaBrown 1 year 42 weeks ago – Made popular 1 year 42 weeks ago
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4

L-NAME Inhibitor

http://www.bocsci.com

L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with Ki of 15 nM, 39 nM and 4.4 μM, respectively.

References:
1,Effect of low doses of L-NAME on methamphetamine-induced dopaminergic depletion in the rat striatum
2,Effect of L-arginine methyl ester (L-NAME) on hormonal profile and estrous cycle length in buffaloes (Bubalus bubalis)

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Created by AdaBrown 1 year 42 weeks ago – Made popular 1 year 42 weeks ago
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4

Ghk-cu peptides

http://www.creative-peptides.com

Copper peptide is a naturally occurring copper complex of a glycyl-L-histidyl-L-lysine peptide. It can promote activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts.

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Created by anniegggg 1 year 44 weeks ago – Made popular 1 year 44 weeks ago
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4

Glycopeptides Synthesis

http://www.creative-peptides.com

Glycopeptide has been widely recognized as peptide that contains carbohydrate moieties (glycans). Due to the nature linkage between glycan and the amino acid residues of peptide, glycopeptides can be classified into three types: N-linked, O-linked and C-linked glycopeptides. Among of them, N-linked glycopeptides are the most common type in nature, which N is referred to the asparagine that attached by the glycan. Glycan of O-linked glycopeptides is commonly linked to the hydroxyl groups of serine and threonine, while sometime also bond to lysine, proline and tyrosine. While the least common C-linked glycopeptides are recognized as the attachment between mannose and tryptophane.

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Created by anniegggg 1 year 44 weeks ago – Made popular 1 year 44 weeks ago
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5

Calcitonin pepitde

http://www.creative-peptides.com

Calcitonin (salmon) is a 32-amino acid polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.

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Created by anniegggg 1 year 44 weeks ago – Made popular 1 year 44 weeks ago
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5

GMP Peptide Synthesis

http://www.creative-peptides.com

We have the capacity to produce GMP peptides, APIs in annual quantities of hundreds of kilograms. The availability of low-cost active pharmaceutical ingredients from CreativePep has had a big impact on the international API manufacturers. Large scale cGMP manufacturing requires a commitment to excellence. Using CreativePep as your contract research organization and contract manufacturing organization, you get more choice, more responsiveness, and more expertise to realize your exciting drug discovery and development support.

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Created by anniegggg 1 year 44 weeks ago – Made popular 1 year 44 weeks ago
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5

IB Schools in Bangalore

https://www.trioworldacademy.com

TRIO World Academy is a global platform for learning global values imparted through excellent education of highest standard. The school educates students from nursery to higher secondary as per Cambridge IGCSE, AS, A-Level Curriculum. We are a Co-Educational International Day and Boarding School in Bangalore, India. We are ranked among the top 10 International Schools in India.

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Created by Anonymous 1 year 44 weeks ago – Made popular 1 year 44 weeks ago
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