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rabbit antibody

http://www.creative-biolabs.com

The rabbit antibody repertoire is an exceptional source for both polyclonal antibodies and monoclonal antibodies that combine high specificity with high avidity and affinity. In addition, rabbits, which belong to the order Lagomorpha (lagomorphs), are evolutionarily distant from mice and rats, which belong to the order Rodentia (rodents).

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Created by candyswift 33 weeks 6 days ago – Made popular 33 weeks 5 days ago
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6

human monoclonal antibodies

http://www.creative-biolabs.com

Creative Biolabs offers an innovative custom service to produce native human monoclonal antibodies through our unique Native™ Antibody Discovery Platform.For technical reasons, current in vitro antibody display methods cannot provide human antibodies with naturally paired heavy chain and light chain. This could potentially lead to the generation of antibody molecules that have suboptimal solubility or other biophysical characteristics.

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Created by candyswift 33 weeks 6 days ago – Made popular 33 weeks 5 days ago
Category: Science   Tags:
5

camel antibodies

http://www.creative-biolabs.com

Camelid, especially camel and llama, is a kind of novel source for the research and development of antibody. Compared with other species, camelid members are the only mammals who can produce not only the conventional antibodies composed of heavy chains and light chains, but also novel antibodies only with heavy chains.

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Created by candyswift 33 weeks 6 days ago – Made popular 33 weeks 5 days ago
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7

What is knob into hole?

http://www.creativebiolabs.net

The knobs-into-holes technique is suitable for heterodimerization immunoglobulin heavy (H) chains with amino acid (AA) changes, which can overcome the mispairing problem. In order to overcome the impurity problem in tri-functional antibody production process, experts introduce a knob into the CH3 of one antibody and a corresponding hole into the CH3 of the other antibody via the alteration of AA respectively.

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Created by candyswift 34 weeks 1 day ago – Made popular 34 weeks 17 hours ago
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8

Antibody&Antigen FAQ

http://www.creative-biolabs.com

What is antibody?
How many kinds of native antibodies exist in vivo?
How does antibody mature in vivo?
Is there any artificial antibody and what are their applications?
What are the applications of antibody in research?
What are the applications of antibody in clinic?
What is the difference between the applications of polyclonal antibody and monoclonal antibody?
What is antigen?
What kind of antigen is suitable for immunization to generate antibody?
How does antibody bind to its target antigen?
How to determine the affinity of certain antibody to antigen?

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Created by candyswift 34 weeks 4 days ago – Made popular 34 weeks 3 days ago
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7

Ecamsule inhibitor

http://www.bocsci.com

Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves/protective clothing/eye protection/face protection.
Synonyms[(2E)-2-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)-2-bicyclo[2.2.1]heptanylidene]methyl]phenyl]methylidene]-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonic acid; 3,3'-(1,4-phenylenedimethylidyne)bis(7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfonic acid); Ecamsule; Mexoryl SX; terephthalylidene dicamphor sulfonic acid; 92761-26-7; AC1O5SNJ; Ecamsule [USAN:USP:INN]; SCHEMBL119994; AKOS024464868;

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Created by AdaBrown 35 weeks 1 day ago – Made popular 35 weeks 1 day ago
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Cariprazine Inhibitor

http://www.bocsci.com

Cariprazine is an orally active D2/D3 dopamine receptor antagonist exhibits high selectivity and affinity to dopamine D3(Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin 5-HT(1A) receptors. It is used as an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression. It has also been used as a potential adjunct in treatment-resistant major depressive disorder.

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Created by AdaBrown 35 weeks 1 day ago – Made popular 35 weeks 1 day ago
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7

Gadobutrol inhibitor

http://www.bocsci.com

Gadobutrol is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). It has a macrocyclic framework and is neutral. It is a water-soluble, highly hydrophilic compound with a partition coefficient between n-butanol and buffer at pH 7.6 of ~ 0.006.

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Created by AdaBrown 35 weeks 1 day ago – Made popular 35 weeks 1 day ago
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7

6-Carboxytetramethylrhodamine

http://www.bocsci.com

6-carboxy derivatives of tetramethylrhodamine is one of the most convenient compounds of Xanthene fluorescent dye tetramethylrhodamine. 6-Carboxytetramethylrhodamine is a long-wavelength dye. Besides that, it also can be used for labeling of biomolecules, e.g., DNA, PNA, and peptides. Fluoresence: λex 543 nm, λem 575 nm in 0.1 M Tris pH 8.0; λex 540 nm, λem 565 nm in methanol; λex 555 nm, λem 580 nm; λex 541 nm, λem 568 nm in DMSO

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Created by AdaBrown 35 weeks 1 day ago – Made popular 35 weeks 1 day ago
Category: Science   Tags:
5

Loratadine Inhibitor

http://www.bocsci.com

Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Reference Reading
1.Effects of Prednisolone on the Pharmacokinetics of Loratadine after Oral and Intravenous Administration of Loratadine in Rats
2.Physicochemical characterization and dissolution enhancement of loratadine by solid dispersion technique

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Created by AdaBrown 39 weeks 6 days ago – Made popular 39 weeks 3 days ago
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