maytansinoid from Creative Biolabs


Maytansinoids are microtubule-targeting agents that share same binding site with vinca and function by depolymerizing microtubules and arresting cells in the mitosis stage. Maytansinoids reveal over 100-fold elevated cytotoxicity in cells than vinca alkaloids, making them suitable candidates in anti-cancer therapies utilizing tissue-specific drug delivery strategies, particularly as ADCs.

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Bella Smith's picture
Created by Bella Smith 26 weeks 6 days ago – Made popular 26 weeks 5 days ago
Category: Medicine   Tags:

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