4

WAY-252623 Inhibitor

http://www.bocsci.com

WAY-252623 (LXR-623) is a highly selective and orally bioavailable synthetic modulator of LXR, which can reduces total serum cholesterol and LDL cholesterol and inhibits lesion growth in models of atherosclerosis. IC50 values= 24 and 179 nM (for LXRβ and LXRα, respectively)

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 2 days ago
Category: Science   Tags:
4

PIK-75 inhibitor

http://www.bocsci.com

PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 2 days ago
Category: Science   Tags:
4

Quizartinib inhibitor

http://www.bocsci.com

Quizartinib is an orally available small molecule with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 2 days ago
Category: Science   Tags:
4

Cyt387 Inhibitor

http://www.bocsci.com

Cyt387, also called Momelotinib, under the IUPAC name N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide, is an ATP competitive inhibitor of JAK1 (IC50 = 11 nM) and JAK2 (IC50 = 18 nM) with potential antineoplastic activity, which may result result in the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 3 days ago
Category: Science   Tags:
4

GW3965 inhibitor

http://www.bocsci.com

GW3965 is a potent, selective LXR agonist for hLXRα and hLXRβ. When screened against a panel of nuclear receptors, it cross-reacted with only the pregnane X receptor (PXR). In Vitro: Recruit the steroid receptor coactivator 1 to human LXRα with EC50 of 125 nM in a cell-free ligand-sensing assay

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 3 days ago
Category: Science   Tags:
5

Epithelial Cells

http://www.creative-bioarray.com

Epithelial cells are arranged in tightly packed layers that line the surfaces and cavities of tissues and organs throughout the body. Of the four major tissue types found in the human and animal body, epithelial cells are by far the most prolific. Epithelial cells also comprise key structures of exocrine and endocrine glands.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 3 days ago
Category: Science   Tags:
8

Human Cardiac Fibroblasts

http://www.creative-bioarray.com

HCF from Creative Bioarray Research Laboratories are isolated from the human heart. HCF-a are cryopreserved at secondary culture and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HCF-a are characterized by immunofluorescent method with antibody to fibronectin. HCF-a are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HCF-a are guaranteed to further expand for 15 population doublings at the condition provided by Creative Bioarray.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 3 days ago
Category: Science   Tags:
7

Endothelial Cells

http://www.creative-bioarray.com

Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. Endothelial cells also generate an antithrombotic surface that facilitates transit of plasma and cellular constituents throughout the vasculature. As a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and inducible metabolic and synthetic functions. The endothelial cell reacts with physical and chemical stimuli within the circulation and regulates hemostasis, vasomotor tone, and immune and inflammatory responses. In addition, the endothelial cell is pivotal in angiogenesis and vasculogenesis.

Read more »
Created by AdaBrown 28 weeks 4 days ago – Made popular 28 weeks 3 days ago
Category: Science   Tags:
9

Bepi-Colombo Mission to Mercury

http://www.bepicolombo.net

BepiColombo is a joint mission the European Space Agency (ESA) and JAXA to the planet Mercury. Get latest news, Updates & all the information of BepiColombo. BepiColombo's main goal is particularly testing since Mercury's circle is so near our star. For more details of BepiColombo mission visit our website now.

Read more »
Created by saurabhdoshi69 30 weeks 4 days ago – Made popular 30 weeks 4 days ago
Category: Science   Tags:
8

Huh7 Hepatoma Cells

http://www.creative-bioarray.com

RPMI Advanced medium supplemented with 2% fetal bovine serum.
Culture Propertiesepithelial-like
Sourceliver
Quality ControlTests for mycoplasma, bacteria and fungi were negative
Frozen with 52.5% RPMI-1640, 40% FBS, 7.5% DMSO at about 4-5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Read more »
Created by AdaBrown 31 weeks 3 days ago – Made popular 31 weeks 2 days ago
Category: Science   Tags:

User login

EzySpot is a news/social bookmarking site.
Enjoy Cool Add-ons & Epic Coupons @GearBest May Madness Sale! Get weekly updated deals for action cameras, smart watches and other cool gears.

Syndicate

Syndicate content