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Significance Of Cow Dung In Hinduism | Suresh Foods

http://sureshfoods.com

Millions of Hindus worship and revere cows. It is one of the animals which is considered sacred in Hinduism. From the Mother to the Goddess.a cow is very auspicious and holds a special significance in Hinduism. It is the sacred animal which provides the life sustaining milk. Cows are held in a superior position in Hinduism as it is one of the animals which has been mentioned in Puranas and mythological stories as well.

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Created by SureshFoods 11 weeks 4 days ago – Made popular 11 weeks 3 days ago
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Best Accounting Assignment Writing Help Online - Ask Tutor Help

https://www.asktutorhelp.com

Asktutorhelp is a best accounting assignment writing help, study writing and paper writing service provider for the college and university students. Our purpose is to provide possible services at the lowest prices to enable every student to be able to use our service. Please do not hesitate to contact us.

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6

Vorinostat Inhibitor

http://www.bocsci.com

Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM.
Reference Reading
1. Clinical pharmacology profile of vorinostat, a histone deacetylase inhibitor
Marian Iwamoto • Evan J. Friedman •Punam Sandhu • Nancy G. B. Agrawal. Cancer Chemother Pharmacol (2013) 72:493–508
Vorinostat is an HDAC inhibitor currently marketed in the United States and other countries for the treatment of cutaneous manifestations in patients with cutaneous T cell lymphoma (CTCL) who have progressive disease, persistent, or recurrent disease following two systemic therapies. Vorinostat inhibits the enzymatic activity of Class I (HDAC1, HDAC2, HDAC3) and Class II (HDAC6) HDACs at nanomolar concentrations (IC50<86 nM). A clinical study of vorinostat in patients with stage Ib and higher CTCL, who had failed to two systemic therapies (one containing bexarotene), demonstrated a 30 % overall objective response. An additional study in refractory CTCL patients demonstrated a similar response rate of 31 %.

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Created by AdaBrown 30 weeks 2 days ago – Made popular 30 weeks 2 days ago
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6

Ethyl 4-aminobenzoate

http://www.bocsci.com

Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops
Reference reading:
1. Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics
In this work, we solubilised the local anaesthetic lidocaine or benzocaine into F127 micelles at varying concentrations. A simple phase diagram of F127 in the presence of lidocaine shows regions of existence of either a sol or a gel state (Fig. 7).

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Created by AdaBrown 30 weeks 2 days ago – Made popular 30 weeks 2 days ago
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6

Simvastatin Inhibitor

http://www.bocsci.com

Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM .
TargetsHMG-CoA Reductase (HMGCR)
Reference Reading
1. Input of selected human pharmaceutical metabolites into the Norwegian aquatic environment
Although we did not detect any ATV metabolites in surface water, interestingly we did detect the presence of the main and active metabolite of the statin prodrug simvastatin (SV); simvastatin hydroxy carboxylic acid (SVA) in four of the surface water and sediments collected from Oslofjord.The surface water samples collected contained SVA at concentrations > LODand up to 66 ng L-1, whilst two sediment samples contained low ng g-1 (dw) concentrations of SVA also. No effluent concentrations of SVA were determined; however, we have previously reported the occurrence of SV at low ng L-1 in VEAS WwTW effluent suggesting from these preliminary data that effluent concentrations of SVA would indeed be higher.

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Created by AdaBrown 30 weeks 2 days ago – Made popular 30 weeks 2 days ago
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6

Misoprostol and Impurities

http://www.bocsci.com

Misoprostol is a cytoprotective prostaglandin PGE1 analogue.

Reference:
1.Second Trimester Medical Termination of Pregnancy with Combined Intracervical and Intravaginal Misoprostol: Comparative Analysis with Intravaginal Misoprostol—A Pilot Study
The authors in this study selected a dose of 600 lg for intravaginal misoprostol for the control group, as this is the dose commonly employed for second trimester termination of pregnancy

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Created by AdaBrown 30 weeks 2 days ago – Made popular 30 weeks 2 days ago
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6

Alfuzosin HCl inhibitor

http://www.bocsci.com

Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).
Molecular Weight 425.91
Molecular Formula C19H28ClN5O4
Adrenergic Receptor
The aim of the present work was to develop simple and sensitive kinetic spectrophotometric methods for the determination of alfuzosin HCl in bulk and in its pharmaceutical preparations using alkaline potassium permanganate as an oxidizing agent.

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Created by AdaBrown 30 weeks 2 days ago – Made popular 30 weeks 2 days ago
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5

humanized monoclonal antibodies

http://www.creative-biolabs.com

Humanization is important for reducing the immunogenicity of monoclonal antibodies derived from xenogeneic sources (commonly rodent) and for improving their activation of the human immune system. Since the development of the hybridoma technology, a large number of rodent monoclonal antibodies with specificity for antigens of therapeutic interest have been generated and characterized.

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Created by candyswift 32 weeks 3 days ago – Made popular 32 weeks 2 days ago
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