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4

WAY-252623 Inhibitor

http://www.bocsci.com

WAY-252623 (LXR-623) is a highly selective and orally bioavailable synthetic modulator of LXR, which can reduces total serum cholesterol and LDL cholesterol and inhibits lesion growth in models of atherosclerosis. IC50 values= 24 and 179 nM (for LXRβ and LXRα, respectively)

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Created by AdaBrown 2 years 44 weeks ago – Made popular 2 years 44 weeks ago
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4

PIK-75 inhibitor

http://www.bocsci.com

PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models.

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Created by AdaBrown 2 years 44 weeks ago – Made popular 2 years 44 weeks ago
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4

Quizartinib inhibitor

http://www.bocsci.com

Quizartinib is an orally available small molecule with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis.

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Created by AdaBrown 2 years 44 weeks ago – Made popular 2 years 44 weeks ago
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9

Bepi-Colombo Mission to Mercury

http://www.bepicolombo.net

BepiColombo is a joint mission the European Space Agency (ESA) and JAXA to the planet Mercury. Get latest news, Updates & all the information of BepiColombo. BepiColombo's main goal is particularly testing since Mercury's circle is so near our star. For more details of BepiColombo mission visit our website now.

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Created by saurabhdoshi69 2 years 46 weeks ago – Made popular 2 years 46 weeks ago
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11

Human Cardiomyocytes

http://www.creative-bioarray.com

Cardiomyocytes are derived from the whole heart (of a single donor) that has been dissociated into single cells and cultured using differential adhesion. These cells are characterized by immunostaining of cardiac sarcomeric actin, myosin heavy chain and other cardiac markers.

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Created by AdaBrown 2 years 47 weeks ago – Made popular 2 years 47 weeks ago
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8

Huh7 Hepatoma Cells

http://www.creative-bioarray.com

RPMI Advanced medium supplemented with 2% fetal bovine serum.
Culture Propertiesepithelial-like
Sourceliver
Quality ControlTests for mycoplasma, bacteria and fungi were negative
Frozen with 52.5% RPMI-1640, 40% FBS, 7.5% DMSO at about 4-5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

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Created by AdaBrown 2 years 47 weeks ago – Made popular 2 years 47 weeks ago
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5

RT-112 tumor cells

http://www.creative-bioarray.com

Established from the transitional cell carcinoma (histological grade G2) excised from a woman (age unknown) with untreated primary urinary bladder carcinoma in 1973; described to form tumors in nude mice. Cytokeratine (4),5,(6), 7, 8, 13, 17, 18, 19, Desmoplakin; DNA-index=2,1.

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Created by AdaBrown 2 years 47 weeks ago – Made popular 2 years 47 weeks ago
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5

Tasimelteon inhibitor

http://www.bocsci.com

Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep–wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved.

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Created by AdaBrown 2 years 48 weeks ago – Made popular 2 years 48 weeks ago
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5

Linaclotide inhibitor

http://www.bocsci.com

Linaclotide is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well.

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Created by AdaBrown 2 years 48 weeks ago – Made popular 2 years 48 weeks ago
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3

Pitavastatin inhibitor

http://www.bocsci.com

Catalog Number147526-32-7
SynonymsNK-104 Calcium
CAS Number147526-32-7
DescriptionPitavastatin calcium is a novel member of the medication class of statins.
Molecular Weight880.98
Molecular FormulaC50H46CaF2N2O8
COAInquire
Targetcholesterol esters

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Created by AdaBrown 2 years 48 weeks ago – Made popular 2 years 48 weeks ago
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