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B-Acute Lymphocytic Leukemia (ALL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033 thelansis.com
B-cell acute lymphoblastic leukemia (ALL) is a type of blood cancer in which many abnormal, immature lymphocytes known as blasts begin to multiply in the bone marrow. Lymphocytes are white blood cells that play a role in the immune response. B-ALL is characterized by the expression of various B–cell-specific antigens, which often include PAX-5, CD19, CD20, CD22, CD24, and CD79a. B-cell ALL is primarily a childhood disease, with approximately 75% of cases being children aged <6 years; however, the majority of B-cell ALL occurs in the <15 years of age; also, the peak of the incidence is seen in people around 40 years. Approximately 20% to 30% of adult acute lymphoblastic leukemias (ALLs) and 5% of pediatric ALLs harbor the Ph-chromosome. This genetic alteration confers a poor prognosis, as defined by shorter remission duration, shorter survival, and higher rates of resistance to standard chemotherapy. CNS involvement is more common in relapsed adult patients. In children, the overall complete remission rate is greater than 95%, and in adults, the rate is 60-85 percent. Relapse occurs in 15 to 20% of children with B-cell ALL, and the prognosis becomes less favorable. Adults with B-cell ALL have a relapse rate of approximately 50%, and a poor prognosis is expected, with a median survival of fewer than six months after relapse.
• In children with ALL, 80% to 85% of ALL consists of early B-cells, and approximately 2% are mature B-cells. In adults with ALL, 75% of cases are early B-cells, and 25% are malignant early T-cells.
Thelansis’s “B-Acute Lymphocytic Leukemia (ALL) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033″ covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential B-Acute Lymphocytic Leukemia (ALL) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of B-Acute Lymphocytic Leukemia (ALL) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
B-Acute Lymphocytic Leukemia (ALL) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: B-Acute Lymphocytic Leukemia (ALL) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033