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Congenital Adrenal Hyperplasia (CAH) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033 thelansis.com
Congenital adrenal hyperplasia (CAH) encompasses seven autosomal recessive disorders resulting from gene mutations that encode enzymes in cortisol production pathways. These enzymes include 21-hydroxylase (21OH), 11β-hydroxylase (11βOH), 17α-hydroxylase (17OH, also known as 17,20-lyase), 3β-hydroxysteroid dehydrogenase type 2 (3βHSD2), steroidogenic acute regulatory protein (StAR), P450 cholesterol side-chain cleavage enzyme (SCC), and P450 oxidoreductase (POR). This genetic variation leads to hormonal imbalances and clinical and biochemical phenotypes in individuals with CAH, which can involve alterations in glucocorticoid, mineralocorticoid, and sex steroid production. The impact of CAH varies among individuals. There are different forms of CAH, with the most common being ‘classic CAH,’ typically diagnosed through newborn screening. Classic CAH is comprised of two subtypes: ‘salt-wasting’ and ‘simple virilizing.’ Salt-wasting CAH is a severe condition requiring immediate treatment, while simple virilizing CAH poses no immediate health risks but necessitates ongoing treatment. Some individuals identified through newborn screening may have milder or ‘non-classic CAH,’ which generally results in fewer health complications. Symptoms of non-classic CAH vary widely from person to person. With appropriate treatment, individuals with CAH can achieve a normal life expectancy. However, uncontrolled CAH can lead to life-threatening acute adrenal insufficiency and an increased risk of comorbidities, including metabolic, cardiovascular, and subfertility issues.
• The prevalence of Congenital adrenal hyperplasia (CAH) ranges from 6 to 8 cases per 100,000 population in the USA.
Thelansis’s “Congenital Adrenal Hyperplasia (CAH) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033″ covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Congenital Adrenal Hyperplasia (CAH) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Congenital Adrenal Hyperplasia (CAH) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Congenital Adrenal Hyperplasia (CAH) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
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