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Obstructive Hypertrophic Cardiomyopathy (oHCM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033 thelansis.com
Hypertrophic obstructive cardiomyopathy (HOCM), once known as idiopathic hypertrophic subaortic stenosis, is a condition commonly encountered. It stands as a significant contributor to sudden cardiac death among young individuals, including athletes, affecting both genders equally across diverse racial backgrounds. The familial form of HOCM follows an autosomal dominant inheritance pattern, making it the most prevalent genetically inherited cardiomyopathy. Additionally, it can manifest in individuals without a familial history due to de novo mutations. HOCM arises from gene mutations responsible for encoding sarcomere proteins, including B-myosin heavy chain, troponin, actin, and titin. These mutations induce structural irregularities in myofibrils and myocytes, potentially resulting in abnormal force generation and conduction issues. Consequently, in the absence of alternative causes, this leads to the characteristic phenotype of asymmetric left ventricular hypertrophy. Classification of HOCM can be based on whether it presents with obstruction or not. Diagnosis primarily relies on 2D echocardiography. Treatment strategies are tailored according to symptom severity. Lifestyle adjustments are advocated for mild cases, emphasizing the avoidance of vigorous physical exertion and heavy lifting. Initial pharmacological management for symptomatic HOCM typically involves beta blockers, although cardiac-selective calcium channel blockers may also be considered. It’s essential to steer clear of ACE inhibitors and nitrates in treatment regimens, as they can exacerbate left ventricular outflow tract obstruction by reducing afterload.
Thelansis’s “Obstructive Hypertrophic Cardiomyopathy (oHCM) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033″ covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Obstructive Hypertrophic Cardiomyopathy (oHCM) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Obstructive Hypertrophic Cardiomyopathy (oHCM) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Obstructive Hypertrophic Cardiomyopathy (oHCM) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
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